Please understand that the recommendations below do not replace medical treatment and do not guarantee a cure. However, they can contribute to a real improvement in health.
Food supplements are no substitute for a varied, balanced diet and a healthy lifestyle.
AHCC (Active Hexose Correlated Compound) is a biotechnological compound derived from the mycelium of Lentinula edodes (shiitake mushroom), developed in Japan and considered one of the most well-studied supplements for immune support. AHCC is used worldwide in oncology, viral infections (including HPV), immune insufficiency, chronic inflammation, and to improve quality of life.
Original AHCC is produced exclusively in Japan by Amino Up, the owner of the patented technology. All genuine AHCC products contain raw material sourced from Amino Up and the list of authorized manufacturers can be consulted officially HERE. Products that do not appear on this list are considered inauthentic or counterfeit.
What is AHCC? Structure, origin and production process
AHCC is an extract obtained by a patented process of cultivation, enzymolysis and ultrafiltration of Lentinula edodes mycelium. It is unique in the world of fungal extracts because:
- contains α-glucans (approx. 74%), which are different from the β-glucans typical of other mushrooms;
- has a very low molecular weight, giving it high absorption and bioavailability;
- has a complex immunomodulatory effect documented in clinical studies.
The composition includes modified oligosaccharides, amino acids, lipids, minerals and mycelium-specific bioactive compounds, resulting in an extremely well tolerated and easily metabolized profile.
What does AHCC contain?
- α-glucans (≈74%) - the main component responsible for immunologic activity.
- Low molecular weight polysaccharides - ensure rapid absorption.
- Amino acids, minerals and natural lipids - support cell metabolism.
- Phenolic compounds - help reduce oxidative stress.
The major difference from other medicinal mushroom supplements is the way it is processed, which removes the insoluble fibers and leaves only the active immunologically active fraction.
Benefits of AHCC - what studies show
1. Powerful immune modulator
AHCC increases the activity and number of immune cells:
- NK (Natural Killer) cells - some studies show increases of up to 300-800%;
- macroface - intensifies phagocytosis;
- dendritic cells - crucial role in antigen presentation;
- T-cells - optimize adaptive response.
2. Cytokine regulation
AHCC stimulates the production of IL-12, IFN-γ and other key anti-viral defense molecules while simultaneously reducing excessive inflammation.
3. Documented antiviral activity
Studies show effects in:
- HPV (human papilloma virus) - some clinical studies show high rates of viral clearance;
- Viral hepatitis;
- Epstein-Barr virus (EBV);
- Flu and recurrent respiratory infections.
4. Oncology support
In Japan, AHCC has been used for over 30 years in hospitals as an adjunct therapy. Observed benefits include:
- reducing the side effects of chemotherapy and radiotherapy;
- increased tolerance to treatment;
- increase energy levels and quality of life;
- improving immune status, essential during treatment.
AHCC clinical trials
There are over 30 human clinical trials published in journals in the fields of immunology, oncology and viral infections. Among the institutions where it has been studied:
- Harvard University
- Yale University
- MD Anderson Cancer Center
- Universities and hospitals in Japan, USA, Korea
Most studies show a significant increase in immune response and an improvement in patients' quality of life.
Common uses of AHCC
- oncology support (for reduced side effects and better immunity);
- HPV infections (support for viral clearance);
- chronic or recurrent viral infections;
- Low immunity or cytokine imbalances;
- systemic inflammation;
- preventing immune ageing (immunosenescence).
AHCC doses - guidelines
- Maintenance / prevention: 500 mg - 1 g/day
- Viral / inflammatory: 1 - 2 g/day
- Oncologic support: 3 g/day (or as recommended by your doctor)
Example products:
- AHCC Mycelcaps: 3 capsules/day
- AHCC MCS / Vitals: 2 capsules/day
AHCC safety
- is considered very safe to take;
- has no major side effects reported;
- is well tolerated even in the long term;
- does not interfere with most cancer treatments.
It is not a drug and does not replace cancer treatments.
Conclusions
AHCC is a unique, highly bioavailable supplement, rigorously studied and widely used for optimizing immunity, supporting oncology patients and managing viral infections. Produced exclusively by Amino Up Japan, the original AHCC remains the gold standard in the field.
Choosing a genuine product is essential for efficiency and safety.
Frequently Asked Questions about AHCC (FAQ)
1. Is AHCC only produced in Japan?
Yes. Original AHCC is manufactured exclusively by Amino Up in Japan. Any other source is unauthentic.
2. How do I check if an AHCC product is original?
The manufacturer must appear on the official Amino Up list: list of authorized manufacturers.
3. What are the benefits of AHCC?
- increases the activity of NK cells and macrophages;
- supports the body in viral infections (HPV, EBV, hepatitis);
- reduces inflammation and fatigue;
- improves tolerance to chemotherapy and radiotherapy;
- optimizes immunity in healthy or stressed people.
4. Does AHCC cure cancer?
No. AHCC is not a drug and does not treat cancer. It is an immune modulator used as a complementary support.
5. Who can take AHCC?
People with low immunity, viral infections, cancer patients undergoing treatment, but also healthy people who want to regulate immunity.
6. Is it safe?
Yes. Studies show that AHCC is well tolerated, even at high doses or long-term.
7. What is the recommended dose?
Between 500 mg and 3 g/day, depending on the objective: maintenance, viral, oncologic support.
8. Can I take AHCC with other supplements?
Yes, AHCC is generally compatible with the usual supplements (vitamins, minerals, medicinal mushrooms). It does not interfere with most oncologic treatments, but discussion with your doctor is recommended.
9. When do the first effects appear?
Usually between 2 and 8 weeks, depending on the body and dose.
10. Can I take AHCC if I am healthy?
Yes. AHCC is also used to maintain immunity, prevent and reduce background inflammation. Details, HERE.
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